Purity: > 95% by SDS-PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT. . Alix, also known as PDCD6IP, is a cytoplasmic protein that interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. It's involved in concentration and sorting of cargo proteins of the multivesicular body for incorporation into intralumenal vesicles that are generated by invagination and scission from the limiting membrane of the endosome. Overexpression of this protein and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death. Recombinant PDCD6IP protein was expressed in E.coli and purified by using conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Programmed cell death 6 interacting protein, AIP1, PDCD6IP, DRIP4, HP95, PDC6I, Programmed cell death 6 interacting protein ALG 2 interacting protein 1, ALG2 interacting protein X, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, KIAA1375, MGC17003, PDCD6 interacting protein, Programmed cell death 6 interacting protein.