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Description
Rabbit Anti-Human CIR1 polyclonal antibody for ELISA, WB. CIR1 (corepressor interacting with RBPJ, 1) is a protein-coding gene. Diseases associated with CIR1 include cryptococcosis, and meningoencephalitis, and among its related super-pathways are Notch signaling pathway and Development NOTCH1-mediated pathway for NF-KB activity modulation. GO annotations related to this gene include RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding transcription factor activity. May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.