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Description
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified. Synonyms: Monoclonal NCKIPSD antibody, Anti-NCKIPSD antibody, NCK interacting protein with SH3 domain antibody, DIP antibody, DIP1 antibody, ORF1 antibody, WISH antibody, AF3P21 antibody, SPIN90 antibody, WASLBP antibody, MGC23891 antibody.
Immunogen
NCKIPSD antibody was raised in mouse using recombinant Human Nck Interacting Protein With Sh3 Domain