Immunohistochemistry: 1:500-1:2,000, Immunoprecipitation: 2-5 μg/mg lysate, Western Blot: 1:2,000-1:10,000
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
BAF57/SMARCE1 Polyclonal Antibody. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Immunogen
n/a
Other Names
SMARCE1; BAF57; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; mammalian chromatin remodeling complex BRG1-associated factor 57; BAF57; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1