Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. FZD4, also known as frizzled-4, is a 7- transmembrane glycoprotein of the Frizzled family within the G-protein coupled receptor superfamily. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. This pathways seem to involve interactions with G-proteins. It is involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Recombinant human FZD4, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.