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Description
RhoA Polyclonal Antibody. RhoA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. It is involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis, and plays an essential role in cleavage furrow formation. RhoA is required for the apical junction formation of keratinocyte cell-cell adhesion, and serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. RhoA stimulates PKN2 kinase activity and may be an activator of PLCE1. It is activated by ARHGEF2, which promotes the exchange o
Immunogen
n/a
Other Names
ARH12, ARHA, RHO12, RHOH12, RHOA, oncogene RHO H12, Aplysia ras-related homolog 12, rho cDNA clone 12, h12, small GTP binding protein RhoA, transforming protein RhoA, ras homolog gene family, member A