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| Antigenic Specificity | RhoB |
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| Clone | 19H1L5 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 μg/mL, Immunofluorescence: 2 μg/mL, Western Blot: 1-2 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RhoB Antibody (19H1L5), ABfinity? Rabbit Monoclonal. Rho-related GTP-binding protein (RhoB) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation. |
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| Immunogen | n/a |
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| Other Names | Rho-related GTP-binding protein RhoB |
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| Gene, Accession # | Entrez: 388; Uniprot: P62745 |
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| Catalog # | 702242 |
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| Price | |
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| Order / More Info | RhoB Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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