Immunohistochemistry: 1:500-1:1000, Western Blot: 0.4 μg/mL
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Description
FAM212A Polyclonal Antibody. FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives. FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics. In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly.
Immunogen
n/a
Other Names
C3orf54, INKA1; uncharacterized protein C3orf54, INCA