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Description
PC4 Polyclonal Antibody. PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Immunogen
n/a
Other Names
Proprotein convertase subtilisin/kexin type 4, KEX2-like endoprotease 3, Neuroendocrine convertase 3, NEC 3, Prohormone convertase 3, Pcsk4, Nec-3, Nec3