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Description
MRGPRX1 Polyclonal Antibody. Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
Immunogen
n/a
Other Names
MRGPRX1, MRGX1, SNSR4, SNSR3, MAS-related GPR, member X1