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Description
MRGPRX3 Polyclonal Antibody. Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
Immunogen
n/a
Other Names
MRGPRX3, MAS-related GPR, member X3, Hdrr1, HDRR2, MRGX3, SNSR1, SNSR2, Mas-related GPCR member X3