Cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 6 nM for cdk1 and cdk5, and 6 - 9 nM for cdk2, depending on binding partner). Selective over a range of other protein kinases (IC50 >10,000 nM). Shown to have antiproliferative properties, mediated by ERK1 and ERK2. Purity 99%. MW (observed): 432.91
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
(2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol. NG 95