Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000
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Description
ARHGAP10 Polyclonal Antibody. GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
Immunogen
n/a
Other Names
GRAF2, PS-GAP, PSGAP, GTPase regulator associated with focal adhesion kinase 2, graf-related protein 2, rho GTPase-activating protein 10, rho-type GTPase-activating protein 10