Recombinant Influenza B virus Non-structural protein 1 (NS)
Description
Purity > 85% as determined by SDS-PAGE. MW: 34.2kDa. Full Length: 1-281aa. N-terminal 6xHis-tagged. Influenza B virus (strain B/Singapore/222/1979). Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins. Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response. Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR. Also binds poly (A) and U6 snRNA.