產(chǎn)品名稱 DIABLO Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號(hào) PA5-19974
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 100 ug
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificityDIABLO
    Clonepolyclonal
    Host SpeciesRabbit
    Reactive Specieshuman, mouse, rat
    Isotypen/a
    Formatpurified
    Size100 ug
    Concentrationn/a
    ApplicationsImmunohistochemistry: 5 μg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 1 μg/mL
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionDIABLO Polyclonal Antibody. The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway. Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases. Smac/DIABLO is expressed in a variety of human and mouse tissues.
    Immunogenn/a
    Other Namesn/a
    Gene, Accession #Entrez: 288753, 56616, 66593; Uniprot: Q9JIQ3, Q9NR28
    Catalog #PA5-19974
    Price
    Order / More InfoDIABLO Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
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