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| Antigenic Specificity | RPC3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 μg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RPC3 Polyclonal Antibody. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3C is a specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. POLR3C may direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. POLR3C may be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. POLR3C plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.POLR3C acts as nuclear and cytosolic DNA |
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| Immunogen | n/a |
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| Other Names | Polymerase (RNA) III (DNA directed) polypeptide C (62kD), RPC3, RPC62 |
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| Gene, Accession # | Entrez: 10623; Uniprot: Q9BUI4 |
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| Catalog # | A303-063A |
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| Price | |
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| Order / More Info | RPC3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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