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Description
PERP Polyclonal Antibody. The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response to cellular stress. A novel gene, PERP, is expressed in a p53-dependent manner and at high levels in apoptotic cells compared with G(1)-arrested cells. PERP induction is linked to p53-dependent apoptosis and is directly activated by p53. These data suggest that PERP is a novel effector of p53-dependent apoptosis.
Immunogen
n/a
Other Names
p53 apoptosis effector related to PMP-22, Keratinocytes-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW