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| Antigenic Specificity | CD71 (Transferrin Receptor) |
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| Clone | MEM-75 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Alexa Fluor 700 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 4 μL/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD71 (Transferrin Receptor) Monoclonal Antibody (MEM-75), Alexa Fluor 700. CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 7037; Uniprot: P02786 |
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| Catalog # | MA5-28599 |
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| Price | |
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| Order / More Info | CD71 (Transferrin Receptor) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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