Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3000
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Description
MSL3 Polyclonal Antibody. This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.