Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000
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Description
TTLL12 Polyclonal Antibody. TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
Immunogen
n/a
Other Names
KIAA0153; Tubulin--tyrosine ligase-like protein 12