Immunohistochemistry: 1:10-1:50, Western Blot: 1:2000
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Description
CD98 Polyclonal Antibody. CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with β1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Immunogen
n/a
Other Names
4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE, 4F2 cell-surface antigen heavy chain, CD98 heavy chain, antigen defined by monoclonal antibody 4F2, heavy chain, antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43, lymphocyte activation antigen 4F2 large subunit, monoclonal antibody 44D7