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Description
SMOC2 Monoclonal Antibody (667713). This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants.
Immunogen
n/a
Other Names
DTDP1, MST117, MSTP117, MSTP140, SMAP2, bA270C4A.1, bA37D8.1, dJ421D16.1, SMAP-2, SMOC-2, SPARC-related modular calcium-binding protein 2, secreted modular calcium-binding protein 2, smooth muscle associated protein 2, smooth muscle-associated protein 2, thyroglobulin type-1 repeat containing protein