Immunofluorescence: Assay Dependent, peptide-ELISA: 1:4000, Western Blot: 1-3 μg/mL
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Description
WNT4 Polyclonal Antibody. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2
Immunogen
n/a
Other Names
WNT4; wingless-type MMTV integration site family, member 4; WNT-4; WNT-4 protein precursor