Flow Cytometry: 1:10-1:50, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
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Description
DcR3 Polyclonal Antibody. This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
Immunogen
n/a
Other Names
DCR3, DJ583P15.1.1, M68, M68E, TR6, decoy receptor 3, decoy receptor for Fas ligand, tumor necrosis factor receptor superfamily member 6B