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Description
DCUN1D1 Polyclonal Antibody. Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
Immunogen
n/a
Other Names
DCNL1, DCUN1L1, RP42, SCCRO, SCRO, Tes3, DCN1-like protein 1, DCUN1 domain-containing protein 1, RP42 homolog, defective in cullin neddylation protein 1-like protein 1, squamous cell carcinoma-related oncogene