Immunocytochemistry: 10 μg/mL, Immunofluorescence: 20 μg/mL, Western Blot: 5-10 μg/mL
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Description
CARD10 Polyclonal Antibody. Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kappa-B. CARD 10 and the related p
Immunogen
n/a
Other Names
BIMP1, CARMA3; Bcl10 binding protein and activator of NFKB; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; carma 3; caspase recruitment domain-containing protein 10