Immunohistochemistry: 2-5 μg/mL, peptide-ELISA: 1:32000, Western Blot: 1-3 μg/mL
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Description
CARD11 Polyclonal Antibody. The protein encoded by this gene belongs to the membrane-associated guanylate kinase family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain . This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphory
Immunogen
n/a
Other Names
CARD11; caspase recruitment domain family, member 11; BIMP3; CARMA1; MGC133069; card-maguk protein 1; bcl10-interacting maguk protein 3