產(chǎn)品名稱 SMURF2 Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號(hào) 711323
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 100 μg
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
    Edit&nbsp
    Antigenic SpecificitySMURF2
    Clone4HCLC
    Host SpeciesRecombinant Rabbit
    Reactive Specieshuman
    IsotypeIgG
    Formatpurified
    Size100 μg
    Concentrationn/a
    ApplicationsImmunocytochemistry: 2 μg/mL, Immunofluorescence: 2 μg/mL, Western Blot: 1-2 μg/mL
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionSMURF2 Antibody (4HCLC), ABfinity? Rabbit Oligoclonal. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3. In this way, SMAD2 may recruit substrates, such as SNON, for ubiquitin-mediated degradation. Enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2
    Immunogenn/a
    Other NamesSMAD Specific E3 Ubiquitin Protein Ligase 2; E3 ubiquitin-protein ligase SMURF2; hSMURF2
    Gene, Accession #Entrez: 64750; Uniprot: Q9HAU4
    Catalog #711323
    Price
    Order / More InfoSMURF2 Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
    產(chǎn)品資料 
    <strong id="itm00"><address id="itm00"></address></strong>
    <th id="itm00"></th>
    <acronym id="itm00"><label id="itm00"></label></acronym>

    3. 

    <th id="itm00"></th>