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Description
PLZF Monoclonal Antibody (Mags.21F7), PE, eBioscience?. This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
Immunogen
n/a
Other Names
Zinc finger and BTB domain-containing protein 16; Zinc finger protein PLZF; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; ZNF145; PLZF; ZBTB16