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Description
P53(Ser20) Polyclonal Antibody. ? Target Background: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex
Immunogen
KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser20. Immunogen Range: 5-55/393