Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000
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Description
CD226 Polyclonal Antibody. DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
Immunogen
n/a
Other Names
adhesion glycoprotein, CD226 antigen, CD226 molecule, DNAM 1, DNAM1, DNAX accessory molecule 1, platelet and T cell activation antigen 1, PTA1, T lineage specific activation antigen 1 antigen, TLiSA1