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| Antigenic Specificity | CD27 |
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| Clone | CLB-27/1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | APC-Alexa Fluor 750 conjugate |
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| Size | 0.5 ml |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD27 Monoclonal Antibody (CLB-27/1), APC-Alexa Fluor 750. CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30. The TNF superfamily members are known for the regulation of cell proliferation and death. In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals. CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 comple |
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| Immunogen | n/a |
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| Other Names | CD27 antigen, CD27L receptor, T cell activation antigen CD27, T cell activation antigen S152, T-cell activation antigen CD27, tumor necrosis factor receptor superfamily member 7 |
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| Gene, Accession # | Entrez: 939; Uniprot: P26842 |
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| Catalog # | MHCD2727 |
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| Price | |
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| Order / More Info | CD27 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19843935 |
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