MYD88, 1-309aa, Human, His tag, E.coli (Denatured)
Description
Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol . Myeloid differentiation primary response gene 88, also known as MYD88, acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Recombinant human MYD88 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Myeloid differentiation primary response protein MyD88, MYD88D