Quinolinate Phosphoribosyltransferase (QPRT) Recombinant, Human
Description
Highly purified. This protein is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Species: Homo sapiens Source: E. coli Primary Sequence (aa): 297 Domain (aa): Full-length Tag/Fusion Partner: T7 Tag Applications: Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Quality Control: SDS-PAGE