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Description
Mouse Anti-ATXN1 Recombinant Antibody (2F5). This product is a mouse antibody that recognizes ATXN1 of human. The antibody 2F5 can be used for immunoassay techniques such as: WB, ELISA, FC, IHC. The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. This protein binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. The
Immunogen
Purified recombinant fragment of human ATXN1 expressed in E. coli