An inhibitor of dopamine uptake; binds to the dopamine transporter (Kd = 27.2 nM); selective for the dopamine transporter over the serotonin and norepinephrine transporters (Kds = 940 and 310 nM, respectively); it increases locomotor activity in mice at 10 mg/kg; induces gnawing in mice (ED50 = 17.1 mg/kg),