An agonist of glucocorticoid and mineralocorticoid receptors (EC50s = 0.26 and 0.494 nM, respectively, in CV-1 cells expressing human receptors); inhibits the growth of UM-UC-3, TCC-SUP, and 5637 urothelial carcinoma cell lines (100 nM); decreases TNF production ex vivo in blood cells collected by BAL from calves with experimentally-induced local lung inflammation (5 mg per animal); impairs cell cycle re-entry of cardiac cells seven days post cryo-injury to the heart and impairs cardiac regeneration in vivo in zebrafish (5 μM)