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Description
Mouse Anti-DOCK2 Recombinant Antibody (7G2). Provided herein is a Mouse monoclonal antibody, which binds to Dedicator Of Cytokinesis 2 (DOCK2). The antibody can be used for immunoassay techniques, such as WB, IHC. DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.
Immunogen
Human recombinant protein fragment corresponding to amino acids 1544-1830 of human DOCK2 (NP_004937) produced in E.coli
Other Names
Dedicator Of Cytokinesis 2; Dedicator Of Cyto-Kinesis 2; Dedicator Of Cytokinesis Protein 2; KIAA0209; IMD40;