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| Antigenic Specificity | ATM |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Serine-protein kinase ATM(ATM) detection. Tested with WB in Human. No cross reactivity with other proteins. ATM(ataxia telangiectasia mutated), also known as TEL1 or TELO1, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. The ATM gene is mapped to chromosome 11q22.3. ATM has an essential role in the reconstitutive capacity of hematopoietic stem cells but is not as important for the proliferation or differentiation of progenitors in a telomere-independent manner. ATM functions directly in the repair of chromosomal DNA double-stranded breaks by maintaining DNA ends in repair complexes generated during lymphocyte gene assembly. |
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| Immunogen | E.coli-derived human ATM recombinant protein (Position: D2870-V3056). Human ATM shares 95% amino acid (aa) sequence identity with mouse ATM. |
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| Other Names | Serine-protein kinase ATM;2.7.11.1;Ataxia telangiectasia mutated;A-T mutated;ATM; |
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| Gene, Accession # | ATM, UniProt: Q13315 |
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| Catalog # | RP1040 |
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| Price | |
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| Order / More Info | ATM Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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