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Description
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. This SMOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-431 amino acids from the C-terminal region of human SMOC2.
Immunogen
Human SMOC2.
Other Names
SMOC2; SMAP2; SPARC-related modular calcium-binding protein 2; Secreted modular calcium-binding protein 2; Smooth muscle-associated protein 2