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Description
CD163 Polyclonal Antibody, Biotin Conjugated. ? Target Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of
Immunogen
KLH conjugated synthetic peptide derived from human CD163. Immunogen Range: 140-170/1156
Other Names
Scavenger receptor cysteine-rich type 1 protein M130; CD163; sCD163; M130