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Description
Mouse Anti-SELP Recombinant Antibody (AK-4). Provided herein is a Mouse monoclonal antibody against Human Selectin P. The antibody can be used for immunoassay techniques, such as FC, IHC, IHC-Fr. SELP is a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
Immunogen
CD62P
Other Names
Selectin P; Platelet Activation Dependent Granule-External Membrane Protein; Selectin P (Granule Membrane Protein 140kDa, Antigen CD62); Leukocyte-Endothelial Cell Adhesion Molecule 3; CD62 Antigen-Like Family Member P; Granule Membrane Protein 140kDa; Granule Membrane Protein 140; GMP-140; LECAM3; PADGEM; GRMP; Selectin P (Granule Membrane Protein 140kD, Antigen CD62);