Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-266) protein (His tag)
Description
HMOX1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is then converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HMOX1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme Oxygenase-1 is involved in the regulation of cardiovascular function and its adaptive response to a variety of stressors. HMOX1 is induced in the colon of ulcerative colitis. HMOX1 is found to overexpress with a higher extent of intraplaque angiogenesis implies a multi-faceted role for HMOX1 in modulating the progression of atherosclerosis. HMOX1 expression reduced LPS-stimulated secretion of MCP-1, IL-6, IL-10, and TNF-alpha in murine and human macrophages Synonyms: HO-1, HSP32, bK286B10, HMOX-1, Heme oxygenase 1, HMOX1, HO, HO1
Size
10 μg
Concentration
n/a
Applications
n/a
Other Names
HMOX1|HO1|MGC132176|wu:fc27c04|zgc:65984|ARABIDOPSIS THALIANA HEME OXYGENASE 1|ATHO1|F18A8.4|F18A8_4|GENOMES UNCOUPLED 2|GUN2|HEME OXYGENASE|HEME OXYGENASE 1|HEME OXYGENASE 6|HY1|HY6|PLASTID HEME OXYGENASE|REVERSAL OF THE DET PHENOTYPE 4|HMOX1D|HO-1|HSP32|bK286B10|D8Wsu38e|Hemox|Hmox|Hsp32|HEOXG|Heox|Ho-1|Ho1|hsp32|Hmox1