Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol. IFN-alpha/beta R1, also known as interferon alpha/beta receptor 1 (IFNAR1), is a member of the class II cytokine receptor family of proteins that form heterodimeric receptor complexes. These receptors are shared and served multiple functions. IFNAR1 and IFNBR1, in association with IFNAR2 and IFNBR2, is required for propagating anti-microbial signal transduction triggered by the type 1 interferons such as IFN-alpha and IFN-beta. Also, binding and activation of it stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Recombinant Human IFN-alpha/beta R1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size
100ug, 50ug, 10ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
IFN-alpha/beta R1, IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, Interferon alpha/beta receptor 1,IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1