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Description
Mouse Anti-PAPPA Recombinant Antibody (10E2). Provided herein is a Mouse monoclonal antibody against Human Pappalysin 1. The antibody can be used for immunoassay techniques, such as ELISA. PAPPA is a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The en
Immunogen
n/a
Other Names
Pappalysin 1; Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease; Pregnancy-Associated Plasma Protein A, Pappalysin 1; Differentially Placenta 1 Expressed Protein; Aspecific BCL2 ARE-Binding Protein 2; IGF-Dependent IGFBP-4 Protease; IGFB