產(chǎn)品名稱 LY2811376 from CAYMAN CHEMICAL COMPANY
    產(chǎn)品貨號(hào) 16712-5
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 5 mg
    產(chǎn)品品牌 CAYMAN CHEMICAL COMPANY
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameLY2811376
    DescriptionA non-peptide inhibitor of BACE1 (IC50 = 239 nM) that demonstrates ~10-fold selectivity over BACE2 and >50-fold selectivity over other aspartyl proteases; decreases Aβ in APP-overexpressing cells and transgenic animal models and reduces C99 and sAPPβ, the two primary APP cleavage products generated by BACE1
    Size5 mg
    Concentrationn/a
    Applicationsn/a
    Other NamesAlzheimer's disease BACE1 inhibitor amyloid-β neurodegeneration protease β-secretase research biochemical inhibit neuroscience BACE-1 accumulation Aβ peptide brain primary cause progression sequential proteolytic cleavage precursor protein APP γ-secretase LY-2811376 non-peptide nonpeptide synthetic APP-overexpressing cells transgenic animal model dose-dependent decrease reduce C99 sAPPβ product
    Gene, Accession, CAS #CAS: 1194044-20-6
    Catalog #16712-5
    Price
    Order / More InfoLY2811376 from CAYMAN CHEMICAL COMPANY
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