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Description
Rabbit Anti-ATR (Phosphorylated S428) Polyclonal Antibody (PTM-CBPAB-0400YC). Provided herein is a Rabbit polyclonal antibody against ATR Serine/Threonine Kinase. The antibody can be used for immunoassay techniques, such as ELISA, IHC. ATR is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.