A selective inhibitor of HDAC3 (IC50 = 289 nM) that alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
HDAC3 inhibitor histone deacetylase tumor multiple myeloma biochemical cancer chromatin research epigenetics modification inhibit HDAC-3 BG-45 class I selectivity HDAC1 HDAC2 HDAC6 HDAC-1 HDAC-2 HDAC-6 bortezomib dose-dependently growth mouse model