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Description
Mouse Anti-PKP1 Recombinant Antibody (PP1-2D6). Provided herein is a Mouse monoclonal antibody against Human Plakophilin 1. The antibody can be used for immunoassay techniques, such as IHC-Fr, ELISA, WB. PKP1 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome.