Solute Carrier Family 47, Member 2 (SLC47A2) (C-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human
Isotype
n/a
Format
serum
Size
100 μL
Concentration
n/a
Applications
Immunohistochemistry (IHC),Western Blotting (WB)
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Description
Function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.Subcellular location: Cell membrane, Multi-pass membrane protein Potential. Note: Localized at the brush border membranes of the proximal tubules.Tissue specificity: Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain. Also known as: MATE-2, Kidney-specific H(+)/organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2.
Immunogen
A synthetic peptide from c-terminal region of human SLC47A2 conjugated to an immunogenic carrier protein was used as the antigen.